ROCK1 (Human) Recombinant Protein (Q01)
产品名称： ROCK1 (Human) Recombinant Protein (Q01)
英文名称： ROCK1 (Human) Recombinant Protein (Q01)
产品编号： H00006093-Q01
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
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- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Human ROCK1 partial ORF ( NP_005397, 401 a.a. - 510 a.a.) recombinant protein with GST-tag at N-terminal.
- Sequence:
- SNRRYLSSANPNDNRTSSNADKSLQESLQKTIYKLEEQLHNEMQLKDEMEQKCRTSNIKLDKIMKELDEEGNQRRNLESTVSQIEKEKMLLQHRINEYQRKAEQENEKRR
- Theoretical MW (kDa):
- 37.84
- Preparation Method:
- in vitro wheat germ expression system
- Purification:
- Glutathione Sepharose 4 Fast Flow
- Storage Buffer:
- 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
- Storage Instruction:
- Store at -80°C. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- 12.5% SDS-PAGE Stained with Coomassie Blue.
- Note:
- Best use within three months from the date of receipt of this protein.
- MSDS:
Download
- Application Image
- Enzyme-linked Immunoabsorbent Assay
- Western Blot (Recombinant protein)
- Antibody Production
- Protein Array
- Entrez GeneID:
- 6093
- GeneBank Accession#:
- NM_005406
- Protein Accession#:
- NP_005397
- Gene Name:
- ROCK1
- Gene Alias:
- MGC131603,MGC43611,P160ROCK,PRO0435
- Gene Description:
- Rho-associated, coiled-coil containing protein kinase 1
- Omim ID:
- 601702
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a protein serine/threonine kinase that is activated when bound to the GTP-bound form of Rho. The small GTPase Rho regulates formation of focal adhesions and stress fibers of fibroblasts, as well as adhesion and aggregation of platelets and lymphocytes by shuttling between the inactive GDP-bound form and the active GTP-bound form. Rho is also essential in cytokinesis and plays a role in transcriptional activation by serum response factor. This protein, a downstream effector of Rho, phosphorylates and activates LIM kinase, which in turn, phosphorylates cofilin, inhibiting its actin-depolymerizing activity. [provided by RefSeq
- Other Designations:
- OTTHUMP00000162514,p160-ROCK
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- Adenocarcinoma
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- Edema
- Genetic Predisposition to Disease
- HIV Infections
- Obesity
- Ovarian Failure, Premature
- Pancreatic Neoplasms
- Polycystic Ovary Syndrome
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- Puberty, Precocious
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- Schizophrenia
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