Anti-TWIST Polyclonal Antibody

品牌：solarbio | 货号：K106441P

商品货号：	商品品牌：	规格	基本售价：	选择规格
K106441P-50ul	solarbio	50ul	960.00元
K106441P-100ul	solarbio	100ul	1600.00元

英文名称 Anti-TWIST Polyclonal Antibody
别名 ACS3;bHLHa38;BPES2;BPES3;CRS;CRS1;CSO;SCS;TWIST
应用 WB
稀释比例 WB 1:3000.
交叉反应 Human Mouse Rat
蛋白分子量 33kDa
Gene ID 7291
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 A synthetic peptide of human TWISTprotein
性状 液体
Public Immunogen Range A synthetic peptide of human TWISTprotein
Subcellular Locations Nucleus
Swiss Prot Q15672
克隆类型 Polyclonal Antibody
背景资料 Acts as a transcriptional regulator. Inhibits myogenesis by sequestrating E proteins, inhibiting trans-activation by MEF2, and inhibiting DNA-binding by MYOD1 through physical interaction. This interaction probably involves the basic domains of both proteins. Also represses expression of proinflammatory cytokines such as TNFA and IL1B. Regulates cranial suture patterning and fusion. Activates transcription as a heterodimer with E proteins. Regulates gene expression differentially, depending on dimer composition. Homodimers induce expression of FGFR2 and POSTN while heterodimers repress FGFR2 and POSTN expression and induce THBS1 expression. Heterodimerization is also required for osteoblast differentiation. Represses the activity of the circadian transcriptional activator: NPAS2-ARNTL/BMAL1 heterodimer

英文名称	Anti-TWIST Polyclonal Antibody
别名	ACS3;bHLHa38;BPES2;BPES3;CRS;CRS1;CSO;SCS;TWIST
应用	WB
稀释比例	WB 1:3000.
交叉反应	Human Mouse Rat
蛋白分子量	33kDa
Gene ID	7291
保存	Store at -20°C. Avoid freeze / thaw cycles.
储存液	Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法	Affinity purification
亚型	IgG
免疫原	A synthetic peptide of human TWISTprotein
性状	液体
Public Immunogen Range	A synthetic peptide of human TWISTprotein
Subcellular Locations	Nucleus
Swiss Prot	Q15672
克隆类型	Polyclonal Antibody
背景资料	Acts as a transcriptional regulator. Inhibits myogenesis by sequestrating E proteins, inhibiting trans-activation by MEF2, and inhibiting DNA-binding by MYOD1 through physical interaction. This interaction probably involves the basic domains of both proteins. Also represses expression of proinflammatory cytokines such as TNFA and IL1B. Regulates cranial suture patterning and fusion. Activates transcription as a heterodimer with E proteins. Regulates gene expression differentially, depending on dimer composition. Homodimers induce expression of FGFR2 and POSTN while heterodimers repress FGFR2 and POSTN expression and induce THBS1 expression. Heterodimerization is also required for osteoblast differentiation. Represses the activity of the circadian transcriptional activator: NPAS2-ARNTL/BMAL1 heterodimer